Daniel Tenant, PhD

Synthesis of N3-Methyluridine- and 2′-O-Alkyl/2′-Fluoro-N3-Methyluridine-Modified Phosphoramidites and Their Incorporation into DNA and RNA Oligonucleotides

Avijit Sahoo, Kiran R Gore*

DOI: doi.org/10.1002/cpz1.70039

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Selective Recognition of the Dimeric NG16 Parallel G-Quadruplex Structure Using Synthetic Turn-On Red Fluorescent Protein Chromophore

Nishant Kumar Choudhary, Shalini Gupta, Gourav Das, Avijit Sahoo, S Harikrishna, Surajit Sinha, Kiran R Gore*

DOI: 10.1021/acs.biochem.4c00407

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Investigating the Effect of Chemical Modifications on the Ribose Sugar Conformation, Watson-Crick Base Pairing, and Intrastrand Stacking Interactions: A Theoretical Approach

Gourav Das, S Harikrishna, Kiran R Gore*

DOI: doi.org/10.1021/acs.jpcb.4c02557

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2′-O-Alkyl-N3-Methyluridine Functionalized Passenger Strand Improves RNAi Activity by Modulating the Thermal Stability

Avijit Sahoo, Shalini Gupta, Gourav Das, Atanu Ghosh, Siddharam Shivappa Bagale, Surajit Sinha, Kiran R. Gore*

DOI: 10.1021/acsmedchemlett.4c00140

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4′-C-Acetamidomethyl-2′-O-methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small Interfering RNAs

Sumit Gangopadhyay, Gourav Das, Shalini Gupta, Atanu Ghosh, Siddharam Shivappa Bagale, Pritam Kumar Roy, Mahitosh Mandal, S Harikrishna, Surajit Sinha, Kiran R Gore*

DOI: doi.org/10.1021/acs.joc.3c02506

 

N3-Methyluridine and 2′-O-Alkyl/2′-Fluoro-N3-Methyluridine Functionalized Nucleic Acids Improve Nuclease Resistance While Maintaining Duplex Geometry

Avijit Sahoo, Gourav Das, Atanu Ghosh, Siddharam Shivappa Bagale, Nishant Kumar Choudhary, S. Harikrishna, Surajit Sinha, Kiran R. Gore*

DOI: 10.1016/j.bmc.2024.117616

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Devising robust hydrophobic MOFs and its membrane for ultra-sensitive aqueous phase detection of antibiotics and toxic nitro-explosives and adsorption of TNP

Debolina Mukherjee , Shyam Chand Pal , Gourav Das, Kiran R. Gore , Madhab C. Das*

DOI: doi.org/10.1016/j.jece.2023.110528

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Synthesis and Structural Analysis of N3-Methyluridine and 2’-Alkoxy/Fluoro-N3-Methyluridine Nucleosides by Using NMR Spectroscopy, X-Ray Crystallography, and Computational Methods

Avijit Sahoo, Gourav Das, Nishant Kumar Choudhary, Dr. S. Harikrishna, Dr. Kiran R. Gore*

DOI: doi.org/10.1002/slct.202301858

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Stereochemistry: A three-dimensional insight. By Anil V. Karnik and Mohammed Hasan, Elsevier, 2021. 594 pp., paperback $ 225. ISBN-978-0-12-821062-8

Ashish Patwari, Kiran R. Gore*

DOI: doi.org/10.1002/chir.23506

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Vinyl substituted triphenylamine based turn-off fluorescent probe for selective and sensitive detection of mercury (II) in water and live cells

Nishant Kumar Choudhary, Lavanya L. Mittapelli, Pritam Kumar Roy, Gourav Das, Mahitosh Mandal, Kiran R. Gore*

DOI: doi.org/10.1016/j.saa.2022.121887

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Influence of Sugar Modifications on the Nucleoside Conformation and Oligonucleotide Stability: A Critical Review

Gourav Das, S. Harikrishna*, Kiran R. Gore*

DOI: doi.org/10.1002/tcr.202200174

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Understanding effect of fluid salinity on polymeric drag reduction in turbulent flows of slickwater fluids.

Navneeth Kumar Korleparaa, Nikhil Patel, Christopher Dilley, Asoke Kumar Deysarkar, Kiran R. Gore, Sandeep D. Kulkarni

DOI: 10.1016/j.petrol.2022.110747

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Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications.

Sumit Gangopadhyay, and Kiran R. Gore*

DOI: 10.1080/15476286.2022.2052641

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Folate Receptor-Mediated Small Interfering RNA delivery: Recent Developments and Future Directions for RNA Interference Therapeutics. Nucleic Acid Therapeutics, 2021, 31, 245-270

Sumit Gangopadhyay, Rahul R. Nikam, and Kiran R. Gore*

DOI: 10.1089/nat.2020.0882

 

Synthesis, Structural, and Conformational Analysis of 4'-C-Alkyl-2'-O-Ethyl-Uridine Modified Nucleosides. European Journal of Organic Chemistry, 2021, 6, 924-932

Rahul R. Nikam, S. Harikrishna, and Kiran R. Gore*

DOI: 10.1002/ejoc.202001348

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LiHMDS: Facile, highly efficient, and metal-free transesterification under solvent-free condition. Catalysis Communications, 2021, 149, 106194-106199

Lavanya L. Mittapelli, Kiran R. Gore*

DOI: 10.1016/j.catcom.2020.106194

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A mild and convenient approach for selective acetonide cleavage involved in carbohydrate synthesis using PPA-SiO2. Journal of Carbohydrate Chemistry, 2020, 39, 63–74

Rahul R. Nikam, and Kiran R. Gore*

DOI: 10.1080/07328303.2019.1708374

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A large Stokes shift fluorogen-activating RNA aptamer. Chemistry-European Journal, 2019, 25, 1931-1935

Christian Steinmetzger, Navaneethan Palanisamy, Kiran R. Gore, Claudia Höbartner*

DOI: 10.1002/chem.201805882

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A turn-on fluorescent GFP chromophore analog for highly selective and efficient detection of H2S in aqueous and in living cells. Sensors and actuators B: Chemical, 2019, 298, 126875

Lavanya L. Mittapelli, Ganesh N. Nawale, Sachin P. Gholap, Oommen P. Varghese, Kiran R. Gore*

DOI: 10.1016/j.snb.2019.126875

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Novel Silylated HBI Analog for Rapid, Selective, and Sensitive Detection of Cyanide in Water and Living Cells. Sensors and actuators B: Chemical, 2018, 265, 257-263

Abhishek L. Mirajkar, Lavanya L. Mittapelli, Ganesh N. Nawale, Kiran R. Gore*

DOI: 10.1016/j.snb.2018.03.068

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Journey of siRNA: Clinical Developments and Targeted Delivery. Nucleic Acid Therapeutics, 2018, 28, 209-224

Rahul R. Nikam, Kiran R. Gore*

DOI: 10.1089/nat.2017.0715

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The N2-Furfural Deoxyguanosine (fdG) Adduct Does Not Alter The Structure of B-DNA. Journal of Organic Chemistry, 2016, 81, 502-511

Prativa P. Godhke, Kiran R. Gore, S. Harikrishna, Biswajit Samanta, Jithesh Kottur, Deepak T. Nair, P.I. Pradeepkumar*

DOI: 10.1021/acs.joc.5b02341 ​

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Unique Structural Features in DNA polymerase IV Enable Efficient Bypass of the N2 Adduct Induced by the Nitrofurazone Antibiotic. Structure, 2015, 23, 56-67

Jithesh Kottur, Amit Sharma, Kiran R. Gore, Naveen Narayanan, Biswajit Samanta, P.I. Pradeepkumar*, Deepak T. Nair*

DOI: 10.1016/j.str.2014.10.019

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Influence of 2'-Fluoro versus 2'-O-Methyl Substituent on the Sugar Puckering of 4'-C-Aminomethyl-uridine. Journal of Organic Chemistry, 2013, 78, 9956-9962

Kiran R. Gore, S. Harikrishna, P.I. Pradeepkumar*

DOI: 10.1021/jo4012333

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Design, Synthesis, Biophysical, and Primer Extension Studies of Novel Acyclic Butyl Nucleic Acid (BuNA). Organic and Biomolecular Chemistry, 2013, 11, 5853-5865

Vipin Kumar, Kiran R. Gore, P.I. Pradeepkumar, Venkitasamy Kesavan*

DOI: 10.1039/C3OB41244J

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Synthesis, Gene Silencing, and Molecular Modelling Studies of 4’-C-Aminomethyl-2’-O-Methyl-Modified Small Interfering RNAs. Journal of Organic Chemistry, 2012, 77, 3233-3245

Kiran R. Gore, Ganesh N. Nawale, S. Harikrishna, Vinita G. Chittoor, Sushil Kumar Pandey, Claudia Höbartner, Swati Patankar, P.I. Pradeepkumar*

DOI: 10.1021/jo202666m

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Incorporation of 4'-C-Aminomethyl-2'-O-Methylthymidine into DNA by Thermophilic DNA Polymerases. Chemical Communications, 2012, 48, 9619-9621

Ganesh N. Nawale, Kiran R. Gore, Claudia Höbartner, P.I. Pradeepkumar*

DOI: 10.1039/C2CC35222B

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